Portal vein thrombosis that successfully treated with low molecular weight heparin in acute pancreatitis.
- Author:
Hoon KO
1
;
Sung Hee JUNG
;
Sang Jeong YOON
;
An Na KIM
;
Byung Min JOHN
;
Gi Young CHOI
;
Jun Hyoung KIM
Author Information
1. Department of Internal Medicine, Eulji University School of Medicine, Daejeon, Korea. ddojam@hanmail.net / jsh@eulji.ac.kr
- Publication Type:Case Report
- Keywords:
Pancreatitis;
Venous thrombosis;
Anticoagulants
- MeSH:
Anticoagulants;
Esophageal and Gastric Varices;
Esophagus;
Hemorrhage;
Heparin;
Heparin, Low-Molecular-Weight*;
Hypertension;
Hypertension, Portal;
Inflammation;
Pancreatitis*;
Pancreatitis, Acute Necrotizing;
Portal Vein*;
Stomach;
Venous Thrombosis*
- From:Korean Journal of Medicine
2005;69(5):541-544
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Portal vein thrombosis is an uncommon cause for presinusoidal hypertension, which results from inherited thrombotic disorder, neoplasm, and intra-abdominal inflammation like pancreatitis. It could develop portal hypertension, culminating in variceal bleeding from esophagus or stomach. One of the medical management of portal vein thrombosis is intravenous heparinization followed by long term oral anticoagulation. Intravenous heparinization using unfractionated heparin requires aPTT monitoring for dose adjustment which is not needed for low molecular weight heparin, and has higher risk of bleeding than using low molecular weight heparin. However, the standard protocol for anticoagulation in portal vein thrombosis has not been determined yet. We experienced a case of portal vein thrombosis in acute necrotizing pancreatitis, which was successfully treated with low molecular weight heparin, as herein reported.
