The value of preoperative clinical and sonographic characteristics of clinically node‐negative papillary thyroid carcinomain predicting central lymph node metastasis
10.3760/cma.j.issn.1004‐4477.2019.08.006
- VernacularTitle:术前临床及超声特征预测临床淋巴结阴性甲状腺乳头状癌中央组淋巴结转移的价值
- Author:
Shangyan XU
1
;
Xiaohong JIA
;
Xiaofeng NI
;
Wei ZHOU
;
Weiwei ZHAN
Author Information
1. 上海交通大学医学院附属瑞金医院超声科 200025
- Keywords:
Ultrasonography;
Papillary thyroid carcinoma;
Central lymph node metastasis
- From:
Chinese Journal of Ultrasonography
2019;28(8):675-679
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the association of preoperative clinical and sonographic characteristics of clinically node‐negative ( cN0) papillary thyroid carcinoma ( PTC) with central lymph node metastasis ( CLNM ) . Methods A total of 514 patients with PTC confirmed by pathology in our hospital were included in the retrospective analysis . Clinical and sonographic characteristics were assessed including age ,gender ,tumor size ,and the distance between the tumor and the capsule . These cases were all diagnosed as cN0 according to clinical and sonography examinations . And the cases were divided into CLNM ( + ) group and CLNM ( －) group based on the pathological results . T hen statistical analysis was used to evaluate the correlation between CLNM and risk factors of cN 0 PTCs . Results ① Of the 514 cN0 PTC cases ,211 cases ( 41 .1% ) were CLNM ( + ) and 303 cases ( 58 .9% ) were CLNM ( －) . ② With the presence of capsule invasion in the ultrasound examination ,the probability of CLNM ( + ) group was higher than that of CLNM ( －) group ( 62 .1% vs 37 .9% ) . ③ In the 364 cases without capsule invasion ,the probability of CLNM ( + ) was significantly increased when the distance between the tumor and the capsule was ＜ 1 .5 mm ( 88 .8% vs 11 .2% ) . ④ M ultivariate analysis showed that risk factors independently associated with CLNM included age ＜45 years old ,tumor maximum diameter ≥10 mm ,and the distance between the tumor and the capsule ＜ 1 .5 mm ,among w hich the distance between the tumor and the capsule ＜1 .5 mm had the highest OR value . Conclusions In cN0 PTC patients ,CLNM is associated with age ,size and the distance between the tumor and the capsule .
