Evaluation of left ventricular myocardial systolic dysfunction in patients with obstructive sleep apnea hypopnea syndrome using three‐dimensional strain echocardiography
10.3760/cma.j.issn.1004‐4477.2019.05.008
- VernacularTitle:超声三维应变技术评价阻塞性睡眠呼吸暂停低通气综合征患者左室心肌收缩功能
- Author:
Jie ZHOU
1
,
2
;
Lixue YIN
;
Yun XU
;
Sijia WANG
;
Bo ZHOU
;
Qiao LU
;
Zhiyu GUO
Author Information
1. 遵义医科大学563000
2. 四川省科学医学院·四川省人民医院超声医学研究所
- Keywords:
Ultrasonography;
Obstructive sleep apnea hypopnea syndrom;
Ventricular function,left;
Myocardial contraction;
Strain
- From:
Chinese Journal of Ultrasonography
2019;28(5):407-413
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate left ventricular myocardial systolic function in patients with obstructive sleep apnea hypopnea syndrome ( OSA HS) with normal left ventricular ejection fraction( LVEF) using three‐dimensional strain echocardiography . Methods One hundred patients with OSA HS were divided into mild group ,moderate group and severe group according to apnea hypopnea index ( A HI) w hile matched with 32 healthy people as control group . T he parameters such as three‐dimensional LVEF ,global longitudinal strain( GLS) ,global circumferential strain( GCS) ,global area strain( GAS) ,global radial strain ( GRS) ,twist and torsion based on standard three‐dimensional echocardiography were measured by three‐ dimensional strain echocardiography , the above parameters among the four groups were compared for difference .Linear correlationship between A HI ,LVEF and the three dimensional strain parameters was analyzed respectively . Results ①T here was no significant difference in three‐dimensional LVEF ,twist and torsion between each groups( P ＞0 .05 ) . ②GLS ,GAS and GRS were lower in mild ,moderate and severe group compared with control group ,decreasing along with the disease severity ( P ＜0 .01 or P ＜ 0 .05 ) . GCS in severe group was lower than that in control group ( P ＜0 .01 ) . ③GLS and GAS in severe group were lower than those in mild group ( all P ＜0 .05) .GRS in moderate and severe group were lower than that in mild group( all P ＜ 0 .05 ) ,GAS ,GRS in severe group was lower than those in moderate group ( P ＜0 .05) . ④T here was a mild correlation between GLS and A HI ( r ＝0 .342 , P ＜0 .01) ,GAS and A HI ( r＝0 .294 , P ＜0 .01) ,GRS and A HI ( r ＝ －0 .411 , P ＜0 .01 ) . T here was a mild correlation between GCS and three‐dimensional LVEF ( r＝ －0 .354 , P ＜0 .01 ) ,GAS and three‐dimensional LVEF ( r ＝ －0 .326 , P ＜0 .01) ,GRS and three‐dimensional LVEF ( r ＝0 .300 , P ＜0 .01) . Conclusions T he left ventricular myocardial systolic function is impaired in all patients with OSA HS even with normal LVEF and the dysfunction is aggravating with the disease severity . Ultrasonic three‐dimensional strain imaging technology can be used to detect the subclinical myocardial systolic dysfunction quantitatively in the early stage of OSA HS patients .
