A Case of Autoimmune Progesterone Dermatitis Presenting as Erythema Multiforme.
- Author:
Nam Hee SUNG
1
;
Tae Han KIM
;
Do Hun KIM
;
Hyoseung SHIN
;
Ai Young LEE
;
Seung Ho LEE
Author Information
1. Department of Dermatology, Dongguk University Ilsan Hospital, College of Medicine, Dongguk University, Goyang, Korea. heydoc@paran.com
- Publication Type:Case Report
- Keywords:
Autoimmune progesterone dermatitis;
Erythema multiforme
- MeSH:
Dermatitis*;
Diagnosis;
Erythema Multiforme*;
Erythema*;
Female;
Hypersensitivity;
Luteal Phase;
Medroxyprogesterone Acetate;
Menstrual Cycle;
Menstruation;
Ovulation;
Progesterone*
- From:Korean Journal of Dermatology
2015;53(8):631-634
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Autoimmune progesterone dermatitis is a rare disorder involving hypersensitivity to progesterone. It is most frequently characterized by recurrent erythema multiforme, eczematous or urticarial eruptions during the luteal phase of the menstrual cycle. It resolves or partially improves after menstruation. Sensitivity is demonstrated by a challenge test with medroxyprogesterone acetate. The therapeutic goal for autoimmune progesterone dermatitis is the suppression of ovulation. Currently, the first-line choice of therapy is a combination oral contraceptive. Here, we report a case of autoimmune progesterone dermatitis that manifested as cyclic bullous erythema multiforme. A reactive intradermal progesterone test confirmed the diagnosis.
