An echocardiographic study of left ventricular torsion in patients with latent obstructive hypertrophic cardiomyopathy
10.3760/cma.j.issn.1004‐4477.2019.04.001
- VernacularTitle:隐匿梗阻性肥厚型心肌病患者左心室扭转功能改变的超声心动图研究
- Author:
Lei ZUO
1
;
Jing WANG
;
Xin MENG
;
Changhui LEI
;
Qianli YANG
;
Nan KANG
;
Fan YANG
;
Lei XU
;
Liwen LIU
Author Information
1. 空军军医大学西京医院肥厚型心肌病诊治中心
- Keywords:
Echocardiography,stress;
Latent left ventricular outflow tract obstruction;
Cardiomyopathy,hypertrophic;
Two‐dimensional strain;
Left ventricular twist
- From:
Chinese Journal of Ultrasonography
2019;28(4):277-282
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the changes of left ventricular torsion function in patients with latent obstructive hypertrophic cardiomyopathy ( HCM ) ,and provide quantitative informations for clinical evaluation of cardiac function . Methods A total of 49 consecutive patients with HCM without left ventricular outflow tract obstruction at rest were enrolled . All subjects underwent exercise stress echocardiography . After exercise left ventricular outflow tract pressure gradient ( LVO T‐PG ) ≥30 mm Hg was positive for exercise stress test ( latent obstruction) ,w hile LVO T‐PG＜ 30 mm Hg was negative for exercise stress test ( non‐obstruction) . An ultrasound system obtained two‐dimensional ultrasound images of resting and moving peaks . The global longitudinal strain ( GLS ) ,global circumferential strain ( GCS ) , global radial strain ( GRS) of the left ventricle 16 segments and left ventricular rotation ,twist were analysis using off‐line EchoPAC software . T he differences of the above parameters were compared between the two groups . Results T here were no significant differences in GLS ,GRS ,GCS and Rotation‐B between the two groups in resting and peak period of exercise ( all P ＞ 0 .05 ) ,GRS in both groups were significantly increased compared with that before exercise ( all P ＜ 0 .05 ) . Compared with the negative exercise stress group ,the left ventricular twist and Rotation‐A were significantly increased in resting and peak period of exercise in the positive exercise stress test group( all P ＜0 .05) . Compared with before exercise ,Rotation‐A and left ventricular twist were significantly decreased in the positive exercise stress test group ( all P ＜0 .05) ,while no significantly difference was found in the negative exercise stress group ( all P ＞ 0 .05 ) . Conclusions Left ventricular torsion function is significantly changed in rest and after exercise in latent obstructive HCM patients ,providing valuable quantitative information for clinical comprehensive evaluation of cardiac function .
