Research progress on autophagic mechanism in acute lung injury/acute respiratory distress syndrome
10.3969/j.issn.1008-9691.2019.02.028
- VernacularTitle:自噬在急性肺损伤/急性呼吸窘迫综合征作用机制中的研究进展
- Author:
Banghai FENG
1
;
Guoyue LIU
;
Song QIN
;
Tao CHEN
;
Miao CHEN
Author Information
1. 遵义医学院附属医院重症医学科二病区
- Keywords:
Autophagy;
Acute lung injury;
Acute respiratory distress syndrome;
Oxidative stress;
Mitochondria
- From:
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
2019;26(2):242-246
- CountryChina
- Language:Chinese
-
Abstract:
Autophagy is a fundamental cellular process that plays a role in the turnover of sub-cellular organelles to protein. The activation of autophagy may prevent the pathophysilogical progression of oxidative stress-induced protein damage or organelle damage. The selective form of autophagy can maintain organelle renewal by degrading damaged proteins. In this article, the research progress on the mechanism of autophagy in acute lung injury/acute respiratory distress syndrome (ALI/ARDS) was summarized in order to understand more deeply on this topic and arouse more researchers to pay attention to the role of autophagy in lung protection of ALI/ARDS.
