Risk factors for positive surgical margin after laparoscopic radical prostatectomy
10.3969/j.issn.1000-8179.2019.06.276
- VernacularTitle:腹腔镜前列腺癌根治术后切缘阳性的相关影响因素分析
- Author:
Zheng ZHANG
1
;
Kenan ZHANG
;
Baoan HONG
;
Jiufeng ZHANG
;
Bowen ZHOU
;
Kan GONG
Author Information
1. 北京大学第一医院泌尿外科
- Keywords:
prostate cancer;
positive surgical margin;
laparoscopy;
prostatectomy
- From:
Chinese Journal of Clinical Oncology
2019;46(6):299-302
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To identify risk factors for positive surgical margin after laparoscopic radical prostatectomy. Method: The study retrospectively analyzed the records of 177 patients with prostate cancer who eventually underwent laparoscopic radical prostatecto-my from January 2016 to December 2017 in Peking University First Hospital. Age, prostate volume, prostate-specific antigen (PSA) be-fore needle biopsy, number of positive cores, positive percentage of needle biopsy and biopsy, and postoperative Gleason scoreand pathological stage were analyzed. Results: The overall positive surgical margin rate was 32.2% (57/177). Age, prostate volume, PSA be-fore needle biopsy, positive percentage of biopsy, and postoperative Gleason score were not significantly different (P>0.05). The study demonstrated significant differences between the number of positive cores, positive percentage of needle biopsy, and pathological stage (P<0.05). Multiple logistic regression revealed that the pathological stage was an independent factor affecting the positive surgi-cal margin rate (odds ratio, 1.616; 95% confidence interval, 1.062-2.459). Conclusions: The number of positive cores, positive percent-age of needle biopsy, and pathological stage significantly correlated with a positive surgical margin. The postoperative pathological T stage is an independent factor affecting positive surgical margins.
