Progress in the diagnosis and treatment of synchronous multiple gastric cancer
10.3969/j.issn.1000-8179.2019.02.825
- VernacularTitle:同时性多发性胃癌的诊疗进展
- Author:
Jiafu JI
1
;
Anqiang WANG
;
Zhaode BU
Author Information
1. 北京大学肿瘤医院胃肠外科
- Keywords:
multiple gastric cancer;
treatment;
prognosis;
heredity
- From:
Chinese Journal of Clinical Oncology
2019;46(2):64-68
- CountryChina
- Language:Chinese
-
Abstract:
Synchronous multiple gastric cancer is a rare condition involving multiple malignant tumors at different sites in the stom-ach. Such cases account for 6%-14% of all gastric cancers. Currently, cases of multiple gastric cancer can be classified by the monoclo-nal or polyclonal nature of the original tumor. Some patients with multiple gastric cancer exhibit hereditary susceptibility and muta-tions in mismatch repair genes. Multiple gastric cancer occurs more commonly among elderly male patients and in the proximal stom-ach at an early stage. No significant differences in vascular invasion, differentiation status, and lymph node metastasis have been iden-tified between solitary and multiple gastric cancers. Several treatment approaches for multiple gastric cancer have been applied clini-cally, including endoscopic resection and subtotal and total gastric resection according to the tumor stages and sites. Further discus-sion is needed regarding the extension of gastric resection for multiple gastric cancer in patients with hereditary susceptibility.
