Diagnostic value of contrast-enhanced ultrasound combined with tumor markers in benign and malignant ovarian tumors
10.3760/cma.j.issn.1008-1372.2019.08.008
- VernacularTitle:超声造影联合肿瘤标志物对卵巢良恶性肿瘤的诊断价值
- Author:
Yiyun XU
1
;
Mang LI
;
Yan CAI
;
Yongjin PENG
;
Yingying YUAN
;
Wenfang WU
;
Chongwen XIE
Author Information
1. 广东省湛江中心人民医院超声医学科 524045
- Keywords:
Ultrasonography;
Contrast media;
Biomarkers,tumor;
Ovarian neoplasms
- From:
Journal of Chinese Physician
2019;21(8):1146-1148
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the diagnostic value of contrast-enhanced ultrasound combined with tumor markers in benign and malignant ovarian tumors.Methods The clinical data of 100 patients with ovarian tumors treated in our hospital from May 2016 to May 2017 were analyzed retrospectively.The parameters of contrast-enhanced ultrasonography (CEUS) for benign and malignant ovarian tumors were analyzed.The levels of tumor markers were measured and the ultrasound imaging was analyzed.Analysis of the detection rate of benign and malignant ovarian tumors by contrast-enhanced ultrasound alone or in combination with tumor markers.Results Compared with benign ovarian tumors,ovarian malignant tumors have the characteristics of uneven enhancement,early onset and peak time of contrast enhancement,and higher rate of enhancement (P < 0.05);compared with benign ovarian tumors,serum CA125 and CA199 levels in patients with ovarian malignant tumors were higher,with significant difference (P < 0.05).The detection rates of contrast-enhanced ultrasound combined with tumor markers were higher than those of ultrasound or tumor markers alone,and were in accordance with pathological criteria.Conclusions The application of combined contrast-enhanced ultrasound and tumor markers in the diagnosis of ovarian benign and malignant tumors has a high detection rate,can significantly improve the accuracy of clinical detection,and provide a strong basis for treatment.