A study on the attention networks dysfunction and its influencing factors in the patients with alcohol use disorder
10.3760/cma.j.issn.1674-6554.2019.08.009
- VernacularTitle:酒精使用障碍患者注意网络功能缺陷及影响因素
- Author:
Rui TAO
1
;
Liangjun PANG
;
Qinqin RUI
;
Yongmei WANG
Author Information
1. 安徽医科大学附属心理医院
- Keywords:
Alcohol use disorder;
Cognitive function;
Attention;
Attention network test
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2019;28(8):716-720
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the impairment of attention network function in male patients with alcohol use disorder(AUD) and the main influencing factors of attention network function. Methods Forty-one patients with AUD after withdrawal therapy and 34 healthy controls (HC) matched with their demograph-ic data were selected as subjects of study. Attention function were assessed by attention network test (ANT). Results Compared with the healthy control group((30. 62±19. 74)ms,(98. 59±1. 46)%),there were sig-nificant differences in the reaction time of alerting network(t=-2. 479,P=0. 015) and the correct rate of the attention network test(t=-2. 074,P=0. 044) in the AUD group((17. 02±26. 42)ms,( 95. 07±10. 73)%). Pearson correlation analysis showed the alert network of AUD was negatively correlated with the age of first drinking(r=-0. 316,P=0. 044) and was positively correlated with the score of Penn alcohol craving scale (PACS) (r=0. 364,P=0. 019). The correct rate of attention network function in patients with AUD was negatively correlated with the years for education ( r=-0. 343, P=0. 028) and years for addiction ( r=-0. 337,P=0. 031). Linear regression analysis showed the attention network function of AUD patients was affected by the age of first drinking(β=0. 432,t=2. 079,P=0. 046),the years for addiction(β=-0. 555,t=-3. 127,P=0. 004) and years for uncontrol drinking(β=0. 309,t=2. 074,P=0. 047). Conclusion The AUD patients were demonstrated deficit in the alerting network. The impairment of attention function of AUD patients were influenced by their drinking condition.
