Antipsychotics and sudden cardiac death risk factors
10.3760/cma.j.issn.1674-6554.2019.06.017
- VernacularTitle:抗精神病药物与心源性猝死风险因素
- Author:
Yinzhao LIU
1
;
Xiangrong ZHANG
Author Information
1. 南京医科大学附属脑科医院老年精神科 210000
- Keywords:
Antipsychotics;
Sudden cardiac death;
Myocardial infarction;
QT interval;
Ve-nous thromboembolism
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2019;28(6):568-572
- CountryChina
- Language:Chinese
-
Abstract:
Antipsychotics treatment significantly increases the risk of sudden cardiac death in psy-chiatric patients,especially in elder patients. This paper reviews the major clinical risk factors of sudden car-diac death including myocardial infarction,QT interval prolongation and venous thromboembolism,as well as discusses the possible pharmacological mechanisms. We should focus on assessing somatic factors at the on-set of treatment and during maintenance therapy,and choose the antipsychotics reasonably to reduce the pos-sibility of sudden cardiac death.
