The study of intertemporal decision-making of mild cognitive impairment patients
10.3760/cma.j.issn.1674-6554.2019.06.008
- VernacularTitle:轻度认知障碍患者的跨期决策研究
- Author:
Zhi GENG
1
;
Xingqi WU
;
Lu WANG
;
Tingting LIU
;
Shanshan ZHOU
;
Kai WANG
;
Ling WEI
Author Information
1. 安徽医科大学第一附属医院神经内科
- Keywords:
Mild cognitive impairment;
Intertemporal choice;
Delay-discount
- From:
Chinese Journal of Behavioral Medicine and Brain Science
2019;28(6):522-526
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore whether the ability of intertemporal choice is impaired in patients with mild cognitive impairment. Methods Twenty-seven patients with mild cognitive impairment and thirty-five healthy controls were recruited in this study. All subjects completed the " delay-discounting" task and the delayed discount rate (K value) was used to evaluate the patients' decision-making ability. Results (1) The delay discount rate(median=0. 0256,P25=0. 016,P75=0. 100) in mild cognitive impairment patients was higher than that of healthy cotrols(median =0. 006,P25=0. 0025,P75=0. 016). There was significant difference in K-value between the two groups ( Z=-2. 988,P<0. 01). ( 2) Spearman correlation analysis showed that the significant negatively correlation between K-value and digital span forward test (r=-0. 389, P=0. 045) in mild cognitive impairment group. Conclusion The ability of intertemporal choices is impaired in patients with mild cognitive impairment and negatively correlated with attention function.
