A Case of Atypical CD30+ Lymphocytic Hyperplasia Following Tick Bite.
- Author:
Mi Sun KIM
1
;
Hong Sun LEE
;
Kun PARK
;
Sook Ja SON
Author Information
1. Department of Dermatology, College of Medicine, Eulji University, Seoul, Korea. kpark@eulji.ac.kr
- Publication Type:Case Report
- Keywords:
Atypical lymphocyte;
CD30+;
Tick bite
- MeSH:
Bites and Stings;
Hodgkin Disease;
Humans;
Hyperplasia;
Killer Cells, Natural;
Lymphoma;
Lymphoma, B-Cell;
Lymphoma, Primary Cutaneous Anaplastic Large Cell;
Lymphomatoid Papulosis;
Middle Aged;
T-Lymphocytes;
Ticks
- From:Korean Journal of Dermatology
2008;46(12):1615-1618
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Since the discovery of the CD30 molecule, its expression has been considered a reliable marker for CD30+ lymphomas, including lymphomatoid papulosis, primary cutaneous anaplastic large cell lymphoma and borderline cases. However, CD30+ cells can be observed in Hodgkin's lymphoma, as well as in T-cell and B-cell lymphomas or NK cell lymphomas. Furthermore, it can also be found in reactive inflammatory disorders or in non-lymphoid neoplasms. It is very important to differentiate between lymphomas and reactive inflammatory disorders using a combination of clinical, histological, phenotypic and molecular analyses. We report a case of atypical CD30+ lymphocytic hyperplasia in a 57-year-old man following tick bite.
