Amniotic Membrane Transplantation for Perforation and Impending Perforation of Cornea: Four Cases.
- Author:
Hyoung Kyun KIM
1
;
Tae Hoon CHOI
Author Information
1. Department of Ophthalmology, Kangdong Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Korea. thc@hallym.or.kr
- Publication Type:Case Report
- Keywords:
Amniotic membrane transplantation;
Corneal perforation;
Descemetocele
- MeSH:
Adrenal Cortex Hormones;
Amnion*;
Anti-Bacterial Agents;
Burns, Chemical;
Cornea*;
Corneal Perforation;
Corneal Ulcer;
Foreign Bodies;
Keratitis;
Keratoplasty, Penetrating;
Nylons;
Ophthalmic Solutions;
Running;
Sutures;
Transplants;
Visual Acuity
- From:Journal of the Korean Ophthalmological Society
2003;44(7):1693-1699
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To report successfully cured four cases of amniotic membrane transplantation(AMT) as a primary procedure in the cornea that was perforated or impending perforation. METHODS: We performed AMT on 1 case of corneal perforation due to chemical burn, 1 case of perforated descemetocele, 1 case of perforated corneal ulcer due to metallic foreign body and 1 case of impending corneal perforation due to recurrent keratitis. Three or four layers of amniotic membrane(AM) that preserved under -70degrees C were applied over the perforation site and anchored with 10-0 nylon interrupted or running sutures. In one case, a large AM piece was used as a temporary patch. After surgery, all cases were treated with systemic antibiotics, antibiotic eyedrops, and topical corticosteroids. RESULTS: Amniotic membrane transplantation was successful in sealing the perforation in all cases. All corneas remained stable and visual acuity improved. There was no infection or rejection postoperatively. CONCLUSIONS: Multilayer amniotic membrane transplantation allowed a successful repair of corneal perforations. This method may be a good alternative to patch graft or penetrating keratoplasty for treating corneal perforations.