The analysis of risk factors for cerebral microbleeds in cerebral infarction patients.
10.3969/j.issn.1002-0152.2019.06.002
- VernacularTitle:脑梗死患者微出血危险因素分析☆
- Author:
Naiqing CAI
1
;
Liju XIE
;
Zhiwen LI
;
Qingxiang ZHANG
;
Sheng ZHANG
;
Dan＇ni WANG
;
Xiaoyan LIU
;
Xinyi DUAN
;
Hong LIN
;
Bin. CAI
Author Information
1. 福建医科大学附属第一医院神经内科(福州350003)
- Keywords:
Cerebral microbleeds;
Acute ischemic stroke;
Risk factor;
eGFR level
- From:
Chinese Journal of Nervous and Mental Diseases
2019;45(6):326-330
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the risk factors of cerebral microbleeds (CMBs) in acute cerebral infarction patients. Methods We consecutively included 255 acute cerebral infarction patients who were admitted in Neurology Department of the First Affiliated Hospital of Fujian Medical University from January 2014 to December 2016. According to the number and location of CMBs, the patients were divided into infratentorial, cortical and deep cerebral groups, each of which included non-mild and moderate-severe subgroups. The differences of the level of glomerular filtration rate (eGFR) and some common arteriosclerotic risk factors were analyzed between subgroups, and the multiple logistic regression analysis was performed. Results A total of 140 subjects (54.9%) had CMBs. In the infratentorial group, the proportion of patients who were with low eGFR level in the moderate-severe CMBs subgroup was higher than in the non-mild CMBs subgroup (P=0.024). The low eGFR level (OR=3.874, 95% CI:1.261～11.901, P=0.018) and the long duration of hypertension (OR=2.128, 95%CI: 1.004～4.510, P=0.018) were the independent risk factors of the moderate-severe infratentorial CMBs. Conclusion The low eGFR level and long duration of hypertension are risk factors for the moderate and severe infratentorial CMBs after acute ischemic stroke.
