Distribution and risk factors of multi drug resistant bacteria in nosocomial infection in Department of Neurosurgery.
10.3969/j.issn.1002－0152.2019.04.005
- VernacularTitle:医院神经外科感染多重耐药菌的临床分布及危险因素分析☆
- Author:
Zhaoyun XIE
1
;
Yu XIONG
;
Jialu QIN
;
Zhonghua LI
;
Chen. QIANG
Author Information
1. 贵州医科大学第三附属医院感染管理科 (都匀558000)
- Keywords:
Mult drug resistant organism;
Clinical features;
Risk factors
- From:
Chinese Journal of Nervous and Mental Diseases
2019;45(4):212-216
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical features and risk factors of multidrug－resistant bacteria (multi drug resistant organisms, MDROs) infection in Department of Neurosurgery, and to provide evidence for the prevention and control of MDRO infection. Methods Data from 437 cases of infection in hospitalized patients on January 2012－2016 year in December Third Affiliated Hospital of Guizhou Medical University were retrospectively analyzed. Patients were divided into MDROs group and non MDROs group based on the results of MDROs detection. Multi factor Logistic regression analysis model was used to analyze risk factors. Results The infection rate of MDROs was 35.51%, and the detection rate of MDROs was 33.23% . ESBLs, CR－AB and MRSA were the most common bacterial species, and the infection of respiratory tract, urinary tract and wound infection were the main infection sites. Multivariate logistic regression analysis showed that hospitalization time ＞20 d, level of consciousness (coma), occupancy of ICU ≥7 d, ventilation (invasive), number of antibiotics used≥3, combined use of antibiotics≥3, mechanical ventilation Time≥7 d were possible risk factors for MDROs infection in neurosurgical patients (P＜0.05). Conclusion The situation of MDROs infection in neurosurgery is severe. To reduce MDROs infection, it is important to shorten unnecessary hospitalization time, promptly assess and transfer out of ICU as soon as possible, improve microbial examination, avoid frequent change of antibiotics or unnecessary use of use of broad－spectrum antibiotics, reduce unnecessary mechanical ventilation time, change to non－invasive ventilation as far as possible when the condition permits, focus on patients with poor consciousness, and prevent aspiration by mistake.
