Study on the attentional network lateralization in patients with bipolar disorder.
10.3969/j.issn.1002-0152.2019.02.004
- VernacularTitle:双相障碍患者注意网络偏侧化研究
- Author:
Xiaoli MIAO
1
;
WANGAnzhen
;
Wen XIE
;
Jianjun GUAN
;
Yanghua. TIAN
Author Information
1. 安徽医科大学第一附属医院神经内科(合肥 230022)
- Keywords:
Bipolar disorder;
Hemispheric asymmetry;
Attentional network
- From:
Chinese Journal of Nervous and Mental Diseases
2019;45(2):81-85
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the abnormality of cerebral laterality of the three attentional networks (alerting, orienting, executive control) in patients with bipolar depression disorder. Methods Patients with bipolar depression disorder (n=28) and healthy controls (n=40) were selected. Lateralized Attention Network Test (LANT) was used to explore the efficiency of the networks in bilateral cerebral hemisphere. Results In the response time (RT), there was a significant interaction between groups and hemispheres in orienting network (F=4.67, P=0.03). The result of post hoc test indicated that the RT in the orienting function was significantly longer in the left hemisphere than in the right in control group (t=-4.47, P＜0.05). There was no significant difference in the orienting network between the left and right hemisphere in patients with the depressive bipolar disorder. Conclusion Attention is impaired in patients with depressive bipolar disorder in which the disappearance of left hemisphere advantage of orienting network is the main manifestation of attention impairments.
