Surveillance of antibiotic resistance in the clinical isolates in Xinhua Hospital Chongming Branch, Shanghai Jiaotong University School of Medicine from 2015 to 2017
10.16718/j.1009-7708.2018.06.011
- VernacularTitle:2015-2017年上海交通大学医学院附属新华医院崇明分院临床常见细菌耐药性监测
- Author:
Minjian QIAN
1
;
Li ZHANG
Author Information
1. 上海交通大学医学院附属新华医院崇明分院检验科
- Keywords:
bacterium;
antimicrobial agent;
resistance surveillance;
carbapenem-resistant Enterobacteriaceae
- From:
Chinese Journal of Infection and Chemotherapy
2018;18(6):621-626
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate antimicrobial susceptibility profile of clinical isolates in Xinhua Hospital Chongming Branch affiliated to Shanghai Jiaotong University School of Medicine for rational use of antibiotics. Methods WHONET 5.6 software was used to analyze the distribution and susceptibility testing data of clinical isolates. Results A total of 5 278 bacterial isolates were collected from 2015 to 2017. The top three bacterial species were Escherichia coli, Klebsiella pneumoniae, and Pseudomonas aeruginosa, accounting for 24.8％, 16.1％ and 8.4％, respectively. The prevalence of major antibiotic-resistant bacteria was increasing. The prevealence of carbapenem-resistant Enterobacteriaceae (CRE) was 0.8％, 3.5％ and 7.0％ in the 3 years. The prevalence of MRSA was 32.4％, 41.9％, and 51.3％, respectively. The prevalence of the Acinetobacter strains resistant to antibiotics, especially to imipenem and meropenem, increased from 20.3％ to 64.6％. No vancomycin-or linezolid-resistant isolates were found in gram-positive bacteria. Conclusions The clinical bacterial isolates show increasing resistance to most antibiotics during the 3-year period in this secondary care general hospital. Especially, carbapenem-resistant Enterobacteriaceae poses a serious threat. Attention should also be paid to surveillance of antimicrobial resistance in secondary care general hospital.
