Research progress of intestinal dysbacteriosis in colorectal cancer and metastasis
10.3760/cma.j.issn.1008-6706.2019.06.032
- VernacularTitle:肠道菌群在结直肠肿瘤发生及转移中的作用研究进展
- Author:
Feng LI
1
;
Jinzhou ZHENG
;
Jianfeng YANG
;
Yunhua QIU
;
Xiaoyun SONG
;
Xiqiu ZHOU
Author Information
1. 上海中医药大学附属龙华医院浦东分院普外科 200126
- Keywords:
Colorectal neoplasms;
Enterobacteriaceae;
Intestinal dysbacteriosis;
Inflammatory response;
Tumor-associated macrophages;
Epithelial-mesenchymal transition
- From:
Chinese Journal of Primary Medicine and Pharmacy
2019;25(6):759-761
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer is one of the most common gastrointestinal malignancies with high incidence rate and mortality rate. Human intestinal microbiota play crucial roles in multiple aspects including immune function, digestion and metabolism.Current research literature suggests that there is a significant connection between intestinal dysbacteriosis and colorectal cancer.However,it is not clear how intestinal dysbacteriosis is involved in the initiation, progress and metastasis of colorectal cancer.In this paper,the influence discussed from three aspects.