Correlation between brainstem infarction and stress induced glucose up-regulation ratio
10.3760/cma.j.issn.1673-4904.2019.08.003
- VernacularTitle:脑干梗死与急性应激性血糖升高率的相关性
- Author:
Yun LUO
1
;
Zheng LI
;
Jiahui ZHANG
;
Jingwei LI
;
Zhengjuan LU
Author Information
1. 南京大学医学院附属鼓楼医院神经内科 210008
- Keywords:
Cerebral infarction;
Brainstem;
Hyperglycemia;
Stress
- From:
Chinese Journal of Postgraduates of Medicine
2019;42(8):678-681
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between the stress induced glucose up-regulation and brainstem infarction. Methods Three hundred and sixty-six patients of cerebral infarction in the department of neurology were included in this study. Stress induced glucose up-regulation was reflected by stress induced glucose up-regulation ratio (SIGUT), and the level of SIGUT was compared between groups of brainstem and non-brainstem infarction. SIGUT was categorized into 4 groups according to the quartiles, and relative variables were compared among 4 groups. The level-risk relationship between high level of SIGUT and brainstem infarction was performed through logistic regression. Results The level of SIGUT was higher in group of brainstem infarction than that in group of non-brainstem infarction: 1.060 ± 0.272 vs.1.159 ± 0.301(P＝0.020). The percent of male, diabetes, brainstem infarction and level of FBG, HbA1c, NIHSS was obviously different in the 4 groups of SIGUT according to the quartiles (P<0.05). High level of SIGUT was correlated to brainstem infarction in the single-factor or multivariable logistic regression adjusted for relative variable (P < 0.05). Conclusions Stress induced glucose up-regulation is correlated to the brainstem infarction, which is prone to happen in brainstem infarction, and the magnitude is more prominent.
