Therapeutic effect and clinical application value of noninvasive positive-pressure ventilation in acute respiratory distress syndrome caused by severe acute pancreatitis
10.3760/cma.j.issn.1673-4904.2019.04.011
- VernacularTitle:无创正压通气在重症急性胰腺炎致急性呼吸窘迫综合征中的治疗效果及临床应用价值
- Author:
Mengran ZHANG
1
;
Mei ZHANG
Author Information
1. 首都医科大学宣武医院消化内科
- Keywords:
Pancreatitis,acute necrotizing;
Respiratory distress syndrome,adult;
Treatment outcome;
Noninvasive positive-pressure ventilation
- From:
Chinese Journal of Postgraduates of Medicine
2019;42(4):335-337
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the therapy effect and clinical value of non-invasive positive-pressure ventilation (NPPV) treatment in acute respiratory distress syndrome (ARDS) caused by severe acute pancreatitis. Methods Data of 22 cases of AP with ARDS who were treated with NPPV were retrospectively analyzed. The oxygenation index (OI), PaO2, PaCO2, respiratory rate (RR) and heart rate (HR) were measured and analyzed before and after NPPV treatment. Results All of cases recovered from ARDS. The PaO2, SpO2 and RR decreased 2 h after NPPV treatment [(81.60 ± 12.56) mmHg (1 mmHg=0.133 kPa) vs. (61.50 ± 5.71) mmHg, (95.66 ± 5.13)% vs. (88.52 ± 4.41)% and (24.49 ± 2.01) times/min vs. (33.37 ± 2.96) times/min] (P<0.05). The OI, PaO2, SpO2 and RR further decreased 12 h after NPPV treatment [(367.89 ± 49.58) mmHg vs. (214.64 ± 20.93) mmHg, (105.19 ± 17.60) mmHg vs. (61.50 ± 5.71) mmHg; 0.991 ± 0.026 vs. 0.885 ± 0.044] (P < 0.05). The OI, PaO2, PaCO2 and SpO2 increased significantly, in contrast, RR and HR descended 24 h after NPPV treatment (P < 0.05). Conclusions NPPV treatment can effectively improve oxygenation of patients with ARDS caused by SAP. NPPV has a good value of clinical application and is worth spreading.
