Pathologic Updates on Antibody Mediated Rejection in Renal Transplantation.
10.4285/jkstn.2013.27.2.42
- Author:
Yeong Jin CHOI
1
Author Information
1. Department of Hospital Pathology, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea. mdyjchoi@catholic.ac.kr
- Publication Type:Review
- Keywords:
Antibodies;
Graft rejection;
Complement C4d;
Transplantation;
Kidney
- MeSH:
Antibodies;
Complement C4b;
Graft Rejection;
Humans;
Inflammation;
Kidney;
Kidney Transplantation;
Microcirculation;
Peptide Fragments;
Rejection (Psychology);
Tissue Donors;
Transplants
- From:The Journal of the Korean Society for Transplantation
2013;27(2):42-48
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Progress in the field of antibody mediated rejection (ABMR) in kidney transplantation has shown a rapid increase during the past two decades. New pathologic entities have emerged and replace old concepts and diagnostic terms. According to newly acknowledged facts discovered by clinicians, researchers, and pathologists all over the world, an updated classification, rather than Banff 07, is needed. In order to improve the diagnostic accuracy for ABMR in clinicians as well as pathologists, recognition and awareness of various conditions such as C4d-negative ABMR, subclinical ABMR, de novo donor specific antibody, microcirculation inflammation, isolated vascular lesion, antibody-mediated transplant arteriopathy, etc. are essentially important.
