Research progress of correlation between high mobility group box 1 and cardiovascular diseases
10.3969／j.issn.1008－0074.2019.03.30
- VernacularTitle:高迁移率族蛋白 1 与心血管疾病相关性的研究进展
- Author:
Fu-Qiang KAN
1
;
Hong-Gang NIE
Author Information
1. 哈尔滨医科大学附属第二医院心内科
- Keywords:
Cardiovascular diseases;
High mobility group proteins;
Atherosclerosis
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2019;28(3):379-382
- CountryChina
- Language:Chinese
-
Abstract:
High mobility group box 1 (HMGB1) protein is released by apoptotic cells and monocytes／macrophages.It plays an important role in mediating inflammation development and promoting tissue repairment and regeneration via combining with corresponding receptors .In recent years ,some researches indicated that HMGB1 possessed im-portant diagnostic and prognostic assessment value for coronary heart disease ,heart failure and myocardial injury etc .The present article summarized research progress of HMGB1 in cardiovascular diseases in recent years .
