Research progress of long noncoding RNA in immune tolerance in heart transplantation
10.3969/j.issn.1008－0074.2019.02.33
- VernacularTitle:长链非编码 RNA 在心脏移植免疫耐受中的研究进展
- Author:
Chunmiao TAN
1
;
Shuo ZHANG
Author Information
1. 哈尔滨医科大学附属第二医院心内科
- Keywords:
Heart transplantation;
RNA,untranslated;
Immune tolerance
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2019;28(2):259-262
- CountryChina
- Language:Chinese
-
Abstract:
Long noncoding RNA (lncRNA) exists widely in organism .It is involved in regulatory function ,including chromatin remodeling ,gene transcription ,RNA splicing and transport of proteins etc .various biological and physi—ological process ,so regulating cell proliferation ,differentiation ,apoptosis ,growth and immune response .Certain results have been achieved in gene imprinting ,cancer diseases ,nervous system disease and immune cell differentia—tion researches about lncRNA ,but there′s few researches about its regulation of immune tolerance in heart trans— plantation .The present article made a review mainly on research progress of lncRNA in immune tolerance in heart transplantation .
