Correlation among plasma NT—proBNP level and echocardiographic indexes in patients with chronic heart disease
10.3969/j.issn.1008－0074.2019.02.10
- VernacularTitle:血浆 NT—proBNP 水平和慢性心衰患者超声心动图指标的相关性
- Author:
Yinghua ZHU
1
Author Information
1. 贵州省纳雍县人民医院心内科
- Keywords:
Heart failure;
Natriuretic peptide,brain;
Echocardiography
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2019;28(2):169-172
- CountryChina
- Language:Chinese
-
Abstract:
Objective :To explore the correlation among plasma level of N terminal pro brain natriuretic peptide (NT—proBNP) and echocardiographic indexes in patients with chronic heart failure (CHF).Methods : Clinical data of 154 CHF patients treated in our hospital were regard as CHF group (NYHA classⅡ ～ Ⅳ).Another 154 cases undergo—ing physical examination in our hospital simultaneously were regarded as normal control group .Serum NT—proBNP level ,left ventricular ejection fraction (LVEF) ,left atrial diameter (LAD) ,left ventricular end—diastolic dimension (LVEDd) ,and heart failure echocardiographic index (HFEI ) were observed and compared between two groups , and correlation among NT—proBNP level and echocardiographic indexes were analyzed .Results : Compared with normal control group ,there were significant rise in serum NT—proBNP level ,LAD ,LVEDd and HFEI ,and signifi—cant reduction in LVEF in CHF group ,and along with NYHA class rose ,there were significant rise in serum NT—proBNP level ,LAD ,LVEDd and HFEI ,and significant reduction in LVEF , P＝0.001 all.Pearson correlation a—nalysis indicated that lgNT—proBNP was significant positively correlated with NYHA class ,LAD ,LVEDd and HFEI ( r＝0. 814～0. 877 , P＜0. 05 all) ,and significant inversely correlated with LVEF ( r＝ －0. 807 , P＝0.009).Con—clusion : NT—proBNP detection combined echocardiography is a frequent method for diagnosis and risk stratification of CHF ,and they are significantly correlated with each other ,so it is worth adopting .
