Research progress about neutrophil extracellular trapping network and histone‐mediated thrombogene‐sis／
10.3969/j.issn.1008－0074.2019.01.32
- VernacularTitle:有关嗜中性粒细胞胞外诱捕网及组蛋白介导的血栓形成研究的进展
- Author:
Chunmeng WU
1
;
Lingbo MENG
Author Information
1. 哈尔滨医科大学附属第二医院心内科
- Keywords:
Thrombosis;
Neutrophils;
Histones
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2019;28(1):126-128
- CountryChina
- Language:Chinese
-
Abstract:
:Platelets and neutrophils are now considered the key factor to thrombus initiation and progression .The present article describes the latest discovery of neutrophil extracellular trapping network (NETs) in thrombogenesis and unknown field to be explore ,including biological process of NET formation (NETosis) ,and how extracellular release of DNA and histone of NETs help coagulation and platelet aggregation .Cell biology of NETosis is still ac‐tively characterized ,which may provide new specific inhibition therapy insights .
