Current research status and progress in molecular subtyping of pancreatic cancer
10.3760/cma.j.issn.1673-9752.2019.07.002
- VernacularTitle:胰腺癌分子分型的研究现状与进展
- Author:
Yinmo YANG
1
;
Zhengkui ZHANG
;
Xiaodong TIAN
Author Information
1. 北京大学第一医院普通外科 100034
- Keywords:
Pancreatic neoplasms;
Pancreatic cancer;
Molecular subtypes;
Molecular targeted therapy;
Progress
- From:
Chinese Journal of Digestive Surgery
2019;18(7):616-620
- CountryChina
- Language:Chinese
-
Abstract:
Rational molecular subtyping of pancreatic cancer based on genome,transcriptome,proteomics and metabolomics data,in combination with systematic biological analysis,have greatly enriched the traditional histopathological typing methods based on morphology.The introduction of molecular subtyping reflects the progress in deep understanding of the essence of tumorigenesis of pancreatic cancer,providing a necessary foundation for the development of molecular targeted therapy and implementation of precision medicine.Therefore,molecular subtyping of pancreatic cancer has broad application prospects.The current article reviews the current research status and recent progress of molecular subtyping of pancreatic cancer,and discusses the clinical significance of different subtyping methods.
