Progress on pathogenesis of capillary leak syndrome
10.3760/cma.j.issn.1673-4912.2019.06.013
- VernacularTitle:毛细血管渗漏综合征发病机制的研究进展
- Author:
Yuanmei CHEN
1
;
Qi ZHANG
Author Information
1. 首都儿科研究所附属儿童医院重症医学科 北京协和医学院
- Keywords:
Capillary leak syndrome;
Pathogenesis
- From:
Chinese Pediatric Emergency Medicine
2019;26(6):461-465
- CountryChina
- Language:Chinese
-
Abstract:
Capillary leak syndrome is a disease characterized by high permeability of vascular endo-thelium leading to anasarca,hypotension,hypoalbuminemia and hemoconcentration,It can cause multiple or-gan failure and high mortality in acute stage. Vascular endothelial hyperpermeability is the core of pathogene-sis of capillary leak syndrome. This article reviewed the latest research progress on the pathogenesis of capil-lary leak syndrome from the aspects of serological mechanism,histological changes and genetic factors.
