Advance of whole brain radiotherapy irradiation of hippocampus in the treatment of small cell lung cancer
10. 11904/j. issn. 1002-3070. 2019. 04. 018
- VernacularTitle:海马区保护治疗小细胞肺癌全脑照射的研究进展
- Author:
Shijia ZHU
1
;
Xiangying XU
Author Information
1. 哈尔滨医科大学附属肿瘤医院放射治疗科(哈尔滨 150081
- Keywords:
Small cell lung cancer;
Whole brain radiotherapy;
Prophylactic carnial irradiation;
Hippocampal protection
- From:
Practical Oncology Journal
2019;33(4):380-383
- CountryChina
- Language:Chinese
-
Abstract:
About 15% to 20% of patients with small cell lung cancer(SCLC)have brain metastases at the time of initial di-agnosis,and more than 80% of patients eventually develop brain metastases. Whole brain radiotherapy(WBRT) is the standard treat-ment for brain metastases in lung cancer. Whole brain prophylactic irradiation(PCI)is an effective treatment for preventing brain me-tastases in SCLC. With the improvement of treatment technology and the standard of treatment,the survival of SCLC patients is pro-longed. The use of spiral tomography(TOMO) technology for hippocampal-protected WBRT in PCI or brain metastasis can reduce neurocognitive impairment and improve the life quality of patient.
