Advanced in the relation between long-chain non-coding RNA CCAT1 and digestive system malignancies
10. 11904/j. issn. 1002-3070. 2019. 04. 015
- VernacularTitle:长链非编码RNA CCAT1与消化系统恶性肿瘤关系的研究进展
- Author:
Jinlu ZHAO
1
;
Guodong LI
;
Ming LIU
Author Information
1. 哈尔滨医科大学第四临床医学院(哈尔滨 150001
- Keywords:
CCAT1;
Long noncoding RNA;
Digestive system cancer;
Cancer biomarker
- From:
Practical Oncology Journal
2019;33(4):367-370
- CountryChina
- Language:Chinese
-
Abstract:
Long non-coding RNAs(lncRNAs)is a functional RNA molecule with a sequence length greater than 200 nucleo-tides that is not translated into a protein. LncRNA is of great value in the clinical application of malignant tumors and is closely related to the diagnosis,prevention,treatment and prognosis of tumors. CCAT1(human colon cancer associated transcript-1)can play a carci-nogenic role by promoting cell proliferation,invasion and migration. CCAT1 can be used as a biomarker for tumor prognosis. In this re-view,the research progress on the relationship between CCAT1 and digestive system malignant tumors is reviewed in recent years,the current status and prospects of malignant tumor treatment by CCAT1 are discussed.
