Comparison of 18 F-FDG PET/CT imaging IHP,Deauville and △SUVmax image analysis methods in the evaluation of the early and mid-stage treatment sensitivity and prognosis in malignant lymphoma
10. 11904/j. issn. 1002-3070. 2019. 02. 012
- VernacularTitle:比较18 F-FDG PET/CT显像IHP、Deauville和△SUVmax在恶性淋巴瘤早中期治疗敏感性判定和预后评估中的应用价值
- Author:
Xuerong LI
1
,
2
;
Hongyan FENG
;
Ying ZHOU
;
Chaoqun LI
;
Xiaoli LAN
;
Lihong BU
Author Information
1. 武汉大学人民医院PET中心(武汉 430060)
2. 武汉大学人民医院分子影像中心
- Keywords:
Lymphoma;
18 F-FDG PET/CT;
IHP;
Deauville 5-point Scoring;
△SUVmax
- From:
Practical Oncology Journal
2019;33(2):160-166
- CountryChina
- Language:Chinese
-
Abstract:
Objective The aim of this study was to explore the values of IHP standard visual judgment,deauville(5-porint scoring and 5-PS)and maximum standard uptake rate(△SUVmax)image methods in the evaluation of early-and mid-term sensi-tivity determination and prognosis in malignant lymphoma patients. Methods A total of 51 patients with lymphoma who met the in-clusion criteria were selected for retrospectively analyses. PET/CT images of patients were analyzed by IHP standard visual judgment and deauville five-point methods. The△SUVmax value of the patient in the early and middle stages of treatment was calculated be-fore treatment, and the optimal cut-off value of PET/CT for early- and mid-term sensitivity determination and prognosis of evalu-ation△SUVmax was obtained by ROC curve. The differences between the diagnostic efficiencies of three methods were compared. The Kaplan-Meier analysis and Cox proportional hazard regression model were used for univariate and multivariate analyses. Results The results of ROC curve analysis showed that PET/CT had the best diagnostic efficiency when△SUVmax was 56. 95% . IHP stand-ard visual judgment,deauville quintile and△SUVmax methods could obtain high sensitivity and negative predictive values for the ear-ly-term treatment of lymphoma treatment. The positive predictive values and accuracy of △SUVmax method were higher than other two methods. Conclusion IHP standard visual judgment,deauville 5,and △SUVmax have high clinical values in the evaluation of early and middle stage of lymphoma treatment and prognosis. They can be used as independent risk factors for prognosis.
