Research progress in the prediction of SNP on radiation-induced lung injury
10.11904/j.issn.1002-3070.2019.01.016
- VernacularTitle:SNP对放射性肺损伤预测作用的研究进展
- Author:
Zhihui HU
1
;
Jing ZHANG
Author Information
1. 石家庄市第一医院肿瘤一科(石家庄 050000
- Keywords:
Radiation-induced lung injury;
Single nucleotide polymorphism;
Lung cancer
- From:
Practical Oncology Journal
2019;33(1):87-91
- CountryChina
- Language:Chinese
-
Abstract:
Radiotherapy is an important treatment for lung cancer. However,the radiation-induced lung injury(RILI)affects some patients and also affects the efficacy of treatment. Therefore,it is very important to identify high-risk patients who may have RI-LI and take action intervention or monitoring. Although the individual difference is often explained by clinical and dosimetric,genetic factors also influence the occurrence of RILI. Currently,there are reports on the relationship between single nucleotide polymorphism (SNP)and RILI. The SNP of these specific genes may become an important predictor of RILI,and thus reduce the incidence of radia-tion-induced lung injury.
