ClinicalvalueofRESOLVE-DWIinthediagnosisandstagingofthyroid-associatedophthalmopathy
10.3969/j.issn.1002-1671.2019.07.006
- VernacularTitle:RESOLVE-DWI在甲状腺相关眼病诊断和分期中的应用价值
- Author:
Wen CHEN
1
;
Hao HU
;
Xiaoquan XU
;
Guoyi SU
;
Huanhuan CHEN
;
Feiyun WU
Author Information
1. (南京医科大学第一附属医院1放射科 江苏 南京 210029)
- Keywords:
thyroid-associatedophthalmopathy;
magneticresonanceimaging;
RESOLVE
- From:
Journal of Practical Radiology
2019;35(7):1050-1053
- CountryChina
- Language:Chinese
-
Abstract:
Objective Toinvestigatetheclinicalvalueofreadoutsegmentationoflongvariableecho-trainsdiffusion-weightedimaging (RESOLVE-DWI)inthediagnosisandstagingofthyroid-associatedophthalmopathy(TAO).Methods Atotalof30consecutivepatientswith TAOand30healthycontrols(HCs)whounderwentRESOLVE-DWIwereenrolledinourstudy.ADCvaluesofextraocularmuscles (superiorrectus,inferiorrectus,medialrectusandlateralrectus)were measuredandcomparedbetween TAOsand HCs,active TAOsandinactiveTAOs,orinactiveTAOsandHCs.ROCanalysiswasperformedtoevaluatethediagnosticvalueofsignificantparametersfor discriminatingactivefrominactiveTAOs.Results TheADCvaluesofallextraocularmusclesinTAOsweresignificantlyhigherthan thoseinHCs(P<0.05).Meanwhile,alltheextraocularmusclesinactiveTAOsshowedsignificantlyhigherADCvaluesthanthose ininactiveTAOs(P<0.05),exceptlateralrectus(P=0.267).WhilstnosignificantdifferenceswerefoundontheADCvaluesofall extraocularmusclesbetweeninactiveTAOsandHCs(P>0.05).ROCanalysisresultsindicatedthattheADCvalueofmedialrectus showedtheoptimalstagingefficacy(cutoffvalue,1.40×10-3 mm2/s;AUC,0.766;sensitivity,92.1%;specificity,59.1%).Conclusion RESOLVE-DWIanditsderivedADCvaluesofextraocularmusclescanassistinthediagnosisofTAO.TheADCvalueofmedial rectushastheoptimalefficacyontheevaluationofitsclinicalactivity.
