EvaluationofMRperfusionweightedimagingofthebrainchronicmountainsickness
10.3969/j.issn.1002-1671.2019.07.004
- VernacularTitle:慢性高原病脑的MR灌注加权成像评价
- Author:
Yuanyuan BAO
1
;
Haihua BAO
Author Information
1. 青海大学附属医院影像中心
- Keywords:
chronicmountainsickness;
brain;
perfusionweightedimaging
- From:
Journal of Practical Radiology
2019;35(7):1042-1045,1049
- CountryChina
- Language:Chinese
-
Abstract:
Objective Toinvestigatethehemodynamicchangesofthegraymatterandwhitematterinpatientswithchronicmountain sickness(CMS).Methods 14CMSpatientsand12healthyvolunteerswererecruitedinthisstudy.Allofthem wereperformedbyroutineMRI andperfusionweightedimaging(PWI)scans.Aftertheappropriatepost-processing,therelevanthemodynamicparametersofdifferent graymatternucleiandwhitematteroffrontallobewereobtained,andthedifferenceofeachvaluebetweenthetwogroupswascompared.Results Therelativecerebralbloodflow (rCBF)decreasedinthebraingraymatterandwhitematterinCMSpatientswhencomparedwith normalgroup(P<0.05)[rCBFofthespleniumofthecorpuscallosum was(40.57±18.89)mL·100g-1·min-1forCMSpatients, and (64.56±18.55)mL·100g-1·min-1fornormalgroup],andatthesametime,meantransittime (MTT)andtimetopeak (TTP)werebothprolonged(P<00.5)[MTTofthespleniumofthecorpuscallosumwas(66.3±19.5)sforCMSpatients,and(48.0±2.17)sfor normalgroup;TTPofthespleniumofthecorpuscallosum was(26.86±4.67)sforCMSpatients,and (23.17±3.01)sfornormal group].Conclusion Collateralcirculation mayexistinCMSpatients’brain.Therearecerebralhemodynamicdifferencesbetween CMSpatientsandhealthyvolunteers.MRPWIisanimportantwayfordiagnosisofCMS.
