The clinical application of DWI signal intensity at different b values and ADC value in diagnosis of prostatic cancer
10.3969/j.issn.1002G1671.2019.06.032
- VernacularTitle:不同b值扩散加权成像信号强度联合表观扩散系数值在前列腺癌诊断中临床应用分析
- Author:
Weihui XIE
1
;
Guojin XIA
;
Honghan GONG
;
Jian JIANG
;
Xianjun ZENG
Author Information
1. 南昌大学医学院
- Keywords:
prostatic cancer;
benign prostatic hyperplasia;
diffusion weighted imaging;
apparent diffusion coefficient;
magnetic resonance imaging
- From:
Journal of Practical Radiology
2019;35(6):981-984,1018
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of DWI and ADC in differential diagnosis of benign prostatic hyperplasia (BPH)and prostatic cancer(PCa).Methods The data of 43 patients with BPH or PCa proven by histopathology were retrospectively reviewed. There were 21 patients with PCa and 22 patients with BPH.All of the patients were examined by DWI at 1.5T MRI.On the DWI,signal intensities in ROI were measured at the b value of 800 s/mm2 and 1 600 s/mm2 ,respectively.On the ADC map,ADC values in ROI were measured.The differences of the ADC values and the signal intensities of DWI were compared between the benign BPH and the PCa by using independent sample tGtest.Diagnostic efficiency of the signal intensity and the ADC value for PCa were analyzed by using ROC curve.Results There were statistically significant differences of the ADC values and the signal intensities of DWI at the b value of 800 s/mm2 and 1 600 s/mm2 between the BPH and the PCa (P＜0.05).The ADC at the b value of 1 600 s/mm2 had the highest diagnostic efficiency,the DWI at the b value of 1 600 s/mm2 took a second place,and the DWI at the b value of 800 s/mm2 was worst.Conclusion DWI and ADC are helpful for the diagnosis of PCa,and ADC at b value of 600 s/mm2 has the highest diagnostic efficiency.
