HistogramanalysisofenhancedT1WIintheidentificationofprimarycentral nervoussystemlymphomaandglioblastoma
10.3969/j.issn.1002-1671.2019.05.005
- VernacularTitle:增强T1WI直方图鉴别原发性中枢神经系统淋巴瘤和胶质母细胞瘤的价值
- Author:
Chen CHEN
1
;
Jingliang CHENG
;
Yong ZHANG
;
Lekai LUO
;
Xin GAO
Author Information
1. 郑州大学第一附属医院磁共振科
- Keywords:
primarycentralnervoussystemlymphoma;
glioblastoma;
histogram;
magneticresonanceimaging
- From:
Journal of Practical Radiology
2019;35(5):704-707
- CountryChina
- Language:Chinese
-
Abstract:
Objective ToinvestigatethevalueofenhancedT1WIhistogramanalysisintheidentificationofprimarycentralnervous systemlymphomas(PCNSL)andglioblastomas(GBM).Methods 41casesPCNSLand30casesofGBM confirmedbypathology wereanalyzedretrospectivelyinourhospital.TheT1WI,T2WI,andenhancedT1 MRimagesofthetwogroupswerecollected,andthe MaZdawasusedtoextracttheregionofinterestROIofthetumor.Thehistogramanalysiswasperformedonthemaximalregionof interestofthetumor.Thehistogramfeaturesofthetumors,includingthemean,variance,skewness,kurtosis,andthe1,10,50,90,and 99percentiles,wereusedtofindsignificantdifferencesbetweenthetwogroups.Results Amongthe9parametersextractedfromhistogram analysis,themean,variance,skewness,1st,10th,and50thpercentileswerestatisticallysignificant (P＜0.05).Therewasnosignificant differenceinkurtosis,90thpercentile,and99thpercentile(P＞0.05).Amongtheseparameters,skewnesswasthemosteffectivein identifyingPCNSLandGBM.TheareaundertheROCcurvewas0.960,whilethesensitivityandspecificitywere80%and100%, respectively.Conclusion Thehistogramanalysiscanprovidemoreinformationaboutquantitativeparameters.Amongthem,theskewness hashighdiagnosticefficiency,andprovidesnewideasandmethodsfordifferentialdiagnosisofPCNSLandGBMinthecentralnervous system.
