Ashort-termoutcomeanalysisoftransarterialchemoembolizationcombinedwith microwaveablationformultinodularhepatocellularcarcinoma
10.3969/j.issn.1002-1671.2019.04.028
- VernacularTitle:经动脉化疗栓塞联合微波消融治疗多结节肝细胞癌的短期疗效分析
- Author:
Qun LI
1
;
Yan WANG
;
Wenhui ZHOU
;
Xueda LI
;
Lili YANG
;
Zixiang LI
Author Information
1. 青岛大学附属医院介入医学中心
- Keywords:
hepatocellularcarcinoma;
multinodularhepatocellularcarcinoma;
microwaveablation;
transcatheterarterialchemoembolization
- From:
Journal of Practical Radiology
2019;35(4):626-629
- CountryChina
- Language:Chinese
-
Abstract:
Objective Toinvestigatetheshort-termefficacyoftranscatheterarterialchemoembolization(TACE)combinedwith microwaveablation (MWA;TACE-MWA)inthetreatmentofmultinodularhepatocellularcarcinoma (HCC).Methods 58patients withmultinodularHCCtreatedintheinterventionalmedicinecenterfromJanuary2015toJanuary2017wereincludedingradeAor B.34cases(groupA)receivedTACEand24cases(groupB)underwentTACE-MWAtherapy.Theshort-termefficacywasevaluatedbyfollow-upandanalysisofthetimetoprogression (TTP),localrecurrencerate,newlesionrate,andpostoperativecomplicationsinboth groups.Results TheTTPinthetwogroupswas38-240 (106.2±63.1)daysand90-630 (328.5±178.8)daysrespectively.The incidenceofpostoperativecomplicationsintwogroupswas2.9% (1/34)and4.2% (1/24)respectivelyI.ngroupA,thelocalrecurrenceratewas 52.9% (18/34)andthenewfocusratewas76% (26/34);inthegroupB,thelocalrecurrenceratewas8.3% (2/24)andthenewfocusratewas 66.7% (16/24).Thedifferenceoflocalrecurrenceratebetweenthetwogroupswasstatisticallysignificant(P<0.05),whiletheincidenceofnew lesionwasnotsignificantlydifferent (P>0.05).Conclusion TACE-MWAissafeandeffectiveinthetreatmentofmultinodular HCC.ComparingwithtraditionalTACEtreatment,TACE-MWAcansignificantlyimprovedTTPandlocalcontrolrate.
