Prevention and Treatment of Traditional Chinese Medicine for Heart Failure Caused by Coronary Heart Disease Based on Endpoint Events: Ideas and Methods of Evidence-Based Optimization
- VernacularTitle:基于终点事件的冠心病心衰中医防治方案循证优化思路和方法
- Author:
Jiayuan HU
1
;
Qianqian DAI
;
Ruijin QIU
;
Yang SUN
;
Xiaoyu ZHANG
;
Guihua TIAN
;
Hongcai SHANG
Author Information
- Keywords: Coronary heart disease; heart failure; traditional Chinese medicine; evidence-based medicine; clinical research; endpoint events
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2018;20(12):2119-2125
- CountryChina
- Language:Chinese
- Abstract: Objective: This paper analyzed the present clinical researches of traditional Chinese medicine (TCM) in the treatment of heart failure caused by coronary heart disease and discusses the ideas and methods of evidence-based optimization. Methods: PubMed, EMBASE, Cochrane Library, CNKI, WanFang, VIP and CBM were searched to screen the clinical studies of TCM for treating heart failure caused by coronary heart disease. The problems and solutions were discussed by evaluating the risk of bias of the studies and analyzing the outcomes compared with the Cochrane systematic reviews of chronic heart failure. Results: A total of 32 clinical researches were included and the methodological quality of the studies was generally low. In addition, few studies assessed the endpoint events, mortality and readmission, as the primary outcomes in their trials, which is significantly different from the outcomes concerned in the Cochrane systematic reviews. Conclusion: It is really critical to improve the methodological quality of the trials and to choose the endpoint events as the primary outcomes in the evidence-based optimization of the prevention and treatment of TCM for heart failure caused by coronary heart disease Chinese medicine.
