Evidence-based Optimization Design and Thinking on TCM Syndrome Differentiation and Treatment Protocol of Stable Angina
- VernacularTitle:冠心病稳定性心绞痛中医辨治方案的循证优化设计与思考
- Author:
Han LI
1
,
2
;
Hongcai SHANG
;
Yang SUN
;
Xiaoyu ZHANG
;
Mingxue ZHANG
Author Information
- Keywords: Stable angina; phlegm and blood stasis syndrome; syndrome differentiation and treatment; pragmatic randomized controlled trial; imaginary thinking
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2018;20(12):2109-2113
- CountryChina
- Language:Chinese
- Abstract: Objectives: To strengthen the causal link between TCM syndrome differentiation and curative effect of stableangina through standardized evidence-based design, measurement and evaluation methods, so as to improve the clinicalevidence of TCM. Methods: Under the framework of the top-level parental design, this study aims at the research purposeof early intervention of TCM in patients with stable angina, and adopts a multicenter practical randomized controlled trial.This study adopts superior design and refines the design points of clinical trials in terms of subject selection, interventionsetting, index system construction, sample size estimation, safety observation, and quality control. Results: The nationalkey research and development plan project, "Study on Evidence-based Optimization of TCM Syndrome and TreatmentProtocol of Stable Angina Pectoris and Cross-Boundary Syndrome"indicated that the clinical research design ofevidence-based medicine and TCM differentiation and treatment was improved. Conclusions: The practical RCT designcan fully reflect the characteristics of TCM differentiation and treatment. The evidence-based design of TCM can providemethodological support for improving the quality of evidence.
