Analysis on DNA Methylation and Its Application in TCM Syndrome Research

VernacularTitle:DNA甲基化及其在中医证候研究中运用研究进展探析
Author: Xiaojuan LI ^{1
,

2} ; Wenqi QIU ; Yueyun LIU ; Jiajia WU ; Zhiwei YAN ; Yanjing HOU ; Jiaxu CHEN
Author Information

1. 暨南大学中医学院方证研究中心广州 510632
2. 北京中医药大学中医学院北京 100029
Keywords: DNA methylation; traditional Chinese medicine syndromes
From: World Science and Technology-Modernization of Traditional Chinese Medicine 2018;20(11):1984-1988
CountryChina
Language:Chinese
Abstract: DNA methylation studies the natural modification of DNA that occurs when the nucleotide sequence is unchanged. At present, DNA methylation is used in the field of biomedicine to focus on the characteristics and regularity of disease-wide genome methylation and the DNA methylation biomarkers for disease. Based on the systematic review of DNA methylation research techniques, this paper summarizes and analyzes the current status of DNA methylation technology in basic research of TCM (traditional Chinese medicine) syndromes, and a suggestion to screen the TCM syndrome biomarkers from whole genome DNA methylation is proposed.