Bibliometric Analysis of Traditional Medicine for Liver Tumor Based on PubMed
- VernacularTitle:基于PubMed数据库的传统医药治疗肝肿瘤文献计量分析
- Author:
Qiuxia LIU
1
;
Jinghui ZHENG
;
Ming DAI
;
Fuli LONG
Author Information
- Keywords: PubMed; liver tumor; traditional medicine; bibliometrics; cluster analysis
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2018;20(9):1515-1522
- CountryChina
- Language:Chinese
- Abstract: In order to provide reference for treatment of liver tumors using traditional Chinese medicine, we analyzed the research status of liver tumor treatment with traditional Chinese Medicine based on PubMed. By the bibliography information concurrence mining system (BICOMB 2013), the literature were collected and analyzed from PubMed database from the day of establishment to 31 October 2017. CytoScape3.6.1 software was used to draw the Co-occurrence analysis chart of high-frequency subject headings and the subheadings, and SPSS17 statistical software was used to cluster the high frequency subject headings. 365 literatures were collected in total. The amount of published articles is increasing year by year. The literatures were mainly in English. From the literature indicating the author's country, we found that 70％ of the top 10 countries and regions which published the most papers were from Asia. Among them, Chinese scholars ranked first. The top 5 of the high-frequency subject headings and the subheadings were Humans, Male, Animals, Liver Neoplasms/drug therapy and Carcinoma, and Hepatocellular/drug therapy. The research focused on the following 9 aspects: metabolism of liver cells, neoplasms, liver cancer pathology, pharmacological efficacy of liver cancer, relationship between cell proliferation and apoptosis and efficacy; xenograft model antitumor assays in mice, pharmacology of antitumor Chinese herbal medicine or phytogenic drugs, the effects of dose-response relationship, cellular activity and signal transduction on drug efficacy, therapeutic uses of traditional and phytotherapy and the outcome and mortality of liver tumor. By the bibliometric analysis in the field of traditional medicine for liver tumor, we can understand the research direction and development status of this field, which can be reference for prevention and treatment of liver cancer with TCM.
