Research Progress on Yueju Pill in the Treatment of Depression and Associated Traditional Chinese Medicine Connotation
- VernacularTitle:越鞠丸治疗抑郁症及其中医内涵研究进展
- Author:
Zhilu ZOU
1
;
Yuxuan ZHANG
;
Gang CHEN
Author Information
- Keywords: Yueju pill; antidepressant effect; drug pair of Fructus Gardeniae and Rhizoma Ligustici Chuanxiong; clinical study
- From: World Science and Technology-Modernization of Traditional Chinese Medicine 2018;20(6):875-879
- CountryChina
- Language:Chinese
- Abstract: Depression has become a serious disease affecting the health of Chinese people. Yueju pill has shown a unique rapid and lasting anti-depression effect, and Yueju pill can rapidly improve Parkinson's disease with depression.The drug pair of Fructus Gardeniae and Rhizoma Ligustici Chuanxiong is necessary for traditional Chinese formula Yueju Pill for antidepressant effect. Recent studies have found the antidepressant effect of Yueju pills at regular doses, and an integrative pharmacological method was adopted to predict the targets and pathways of Yueju pill and explore its molecular mechanism for depression. In recent years, there has been an increasing number of clinical studies on the treatment of depression with Yueju pills and significant therapeutic effects. A new clinical study found that Yueju pill may have antidepressant effects and increase serum BDNF concentration. This paper reviewed the recent research progress of Yueju pill in the treatment of depression in recent 5 years.