Two cases of granular cell tumor of the breast

VernacularTitle:乳腺颗粒细胞瘤二例分析
Author: Yongxing CHI ¹ ; Chaoyang XU ; Wei CHEN ; Liming HUANG
Author Information

1. 绍兴市人民医院(浙江大学绍兴医院)乳腺甲状腺外科 312000
Keywords: Breast tumor; Granular cell tumor
From: Chinese Journal of Endocrine Surgery 2019;13(4):351-352
CountryChina
Language:Chinese
Abstract: To investigate the clinicopathologic features of granular cell tumor(GCT) of the breast in order to make a diagnosis and give treatment strategy of this disease.Two cases of granular cell tumor (GCT) of the breast were reported,and the clinical presentation,pathological examination and surgical procedure were analyzed.Clinical presentations were atypical,and the tumor was characterized by clear or ill-defined boundary,abundant cytoplasm,full of eosinophilic granular,and infiltrative growth.Immunohistochemical study revealed that tumor cells were positive with S-100,CD68 and vimentin but negative with cytokeratin (CK) and epithelial membrane antigen(EMA).GCT of the breast is rare,most of which is benign tumor that may be misdiagnosed as malignancy.Wide resection is the main curative treatment.The prognosis is good.The understanding of this disease should be strengthened to avoid being operated excessively.Long-term follow-up should be performed.