Gold standard for primary aldosteronism subtype diagnosis: adrenal vein sampling
10.3760/cma.j.issn.1674-6090.2019.04.019
- VernacularTitle:原发性醛固酮增多症亚型诊断金标准——分侧肾上腺静脉采血
- Author:
Shengzhuo LIU
1
;
Qiang DONG
;
Tao CHEN
;
Liang ZHOU
;
Zhihong LIU
;
Yuchun ZHU
Author Information
1. 四川大学华西医院泌尿外科 610041
- Keywords:
Primary aldosteronism;
Adrenal vein sampling;
Aldosterone producing adenoma
- From:
Chinese Journal of Endocrine Surgery
2019;13(4):343-345
- CountryChina
- Language:Chinese
-
Abstract:
Adrenal vein sampling (AVS),as the gold standard of subtype diagnosis for primary aldosteronism,can directly detect the hormone concentration in adrenal vein by adrenal vein cannulation.Adrenal tumor can be categorized into no function adenoma,adrenal carcinoma,aldosterone producing adenoma (APA),cortisol producing adenoma (CPA) and pheochromocytoma.Traditionally,peripheral blood hormone testing and image examination were performed to make functional diagnosis of adrenal tumor,which exhibits low specificity and sensitivity.On the contrary,AVS can help make a distinct lateralization diagnosis according the aldosterone concentration of each gland,even in the condition of bilateral adrenal tumor and early stage tumor,which is difficult to make functional lateralization diagnosis by traditional methods.AVS can be categorized into simultaneous sampiing and sequencing sampling,according to the order of sampling.According to using adrenocorticotropic hormone (ACTH) or not,AVS can be categorized into no stimulus sampling and post-stimulus sampling.
