Clinical analysis of differentiated thyroid carcinoma in children and adolescent: 75 cases
10.3760/cma.j.issn.1674-6090.2019.04.009
- VernacularTitle:儿童及青少年分化型甲状腺癌75例临床分析
- Author:
Xiaoshan QIN
1
;
Hao ZHANG
;
Ping ZHANG
;
Wenwu DONG
;
Liang HE
;
Ting ZHANG
;
Wei SUN
Author Information
1. 中国医科大学附属第一医院甲状腺外科 沈阳 110001
- Keywords:
Differentiated thyroid carcinoma;
Children and adolescent;
Bilateral location;
Lymph node metastasis
- From:
Chinese Journal of Endocrine Surgery
2019;13(4):301-304
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical characters and treatment strategies of differentiated thyroid carcinoma in children and adolescent.Methods The clinical data of 75 cases of thyroid carcinoma in children and adolescents(≤ 18 years old)from Jan.2004 to Mar.2017 in the First Hospital of China Medical University were retrospectively analyzed.Clinical pathology characters and prognosis between patients ＜13 years old (group A) and those ≥ 13 years old (group B) were compared.Results There were 74 cases with papillary carcinoma and 1 with follicular carcinoma.The rate of lateral neck lymph node metastasis(100％ vs 54.5％,x2=6.818,P=0.025) and bilateral location (55.6％ vs 18.2％,x2=6.311,P=0.037) in group A were higher than in group B.There were no significant differences in central lymph nodes metastasis (88.9％ vs 69.7％,x2=1.758,P=0.420),gender composition ratio (22.2％ vs 31.8％,x2=0.343,P=0.841),extra-thyroid extension (33.3％ vs 18.2％,x2=1.136,P=0.534),distant metastasis(11.1％ vs 1.5％,x2=2.810,P=0.566) and recurrent disease(25％ vs 7.8％,x2=1.141,P=0.183) between the two groups.Conclusions Papillary carcinoma is the most common pathology type in children and adolescent thyroid carcinoma.Patients＜13 years old are more likely to present lateral neck lymph node metastasis and bilateral location.
