The value of ultrasound gray scale ratio in the diagnosis and differential diagnosis in papillary thyroid carcinoma with different sizes
10.3760/cma.j.issn.1674-6090.2019.03.011
- VernacularTitle:超声灰阶比值在甲状腺乳头状癌诊断与鉴别诊断中的价值
- Author:
Chenke XU
1
;
Weibin LI
;
Zhijiang HAN
;
Lifang YU
;
Mingkui LI
;
Zhikai LEI
Author Information
1. 浙江大学医学院附属杭州市第一人民医院超声科 310006
- Keywords:
Ultrasound gray scale ratio;
Papillary thyroid carcinoma;
Nodular goiter;
Thyroid nodules
- From:
Chinese Journal of Endocrine Surgery
2019;13(3):224-228
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the value of ultrasound gray scale ratio (UGSR) in the diagnosis and differential diagnosis of papillary thyroid carcinoma(PTC) with different sizes.Methods A retrospective study was made in 702 patients with 1107 nodules which were confirmed by surgery in the Department of Oncology or fineneedle aspiration of HangZhou First people's Hospital,Zhejiang University of medical school from Jan.2016 to Oct.2017.All the thyroid nodules were divided into three groups:D≤ 1 cm group,1＜D≤2 cm group and ＞2 cm group according to their sizes.The UGSR of the PTC and NG were obtained through the RAD info system.Their differences were analyzed and ROC was established to confirm the optimal threshold in the differential diagnosis between PTC and NG among the groups.Results There were 483 PTC and 624 NG in this study.The UGSR of D≤ 1 cm group,1＜D≤2 cm group and ＞2 cm group of PTC and NG were (0.48±0.12) vs (0.76±0.22)(t=33.21,P=0.00);(0.52±0.17) vs(0.80±0.21)(t=1.30,P=0.00) and (0.63±0.20) vs(0.89±0.24)(t=3.58,P=0.00) respectively.The area under the ROC of UGSR in the differentiation of PTC and NG in the three groups were 0.873,0.840 and 0.811 respectively.The Youden indexes were greatest (0.631,0.536 and 0.535 respectively),when the cut-offs of the UGSR were 0.682,0.652 and 0.831 respectively.The sensitivity and specificity to diagnose PTC were 94.8％ and 68.0％,75.0％ and 78.6％,80.3％ and 73.2％ respectively in the three groups.Conclusions The best UGSR value of PTC was variant in thyroid nodule with different size.Recognition of these differences accurately could improve the pre-operative diagnostic accuracy of PTC.Also the method is simple to operate and easy to apply.
