Molecular Typing and Drug Resistance of Salmonella Typhimurium in Yunnan Province

VernacularTitle:云南省鼠伤寒沙门氏菌PFGE分子分型及耐药情况
Author: Yun-Ping TIAN ¹ ; Li JIN ; Jiang ZHAO ; Xiang REN ; Jian-Wen YIN
Author Information

1. 云南省疾病预防控制中心
Keywords: Salmonella typhi; PFGE; Drug resistance
From: Journal of Kunming Medical University 2018;39(8):23-27
CountryChina
Language:Chinese
Abstract: Objective To understand the molecular typing and drug resistance of Salmonella typhimurium in Yunnan Province, to provide scientific basis for preventing and controlling diseases caused by Salmonella typhimurium. Methods Molecular typing was carried out according to Salmonella PFGE typing technology published by Pulse Net China. The MIC value of the drug sensitive plate was obtained from the analysis of the instructions, and the results of S, I and R were obtained according to the corresponding standards of CLSI.Results The 68 strains salmonella typhimurium in Yunnan Province showed 53 types of PFGE. The drug resistance rate of the 68 strains of salmonella typhimurium was the highest for the compound sulfonamide (SXT), 45.59％, and the most sensitive to imipenem (IMP), among which one strain was resistant to 11 of the14 antibiotics. Conclusion The molecular typing of salmonella typhimuriumin in Yunnan province is diverse.Compound sulfonamide is the most resistant antibiotic of Salmonella typhimurium in this region. Multiple drug resistance of Salmonella typhimurium in this region is atypical.