Expression of IL-17 in Patients with Both PE and OSAHS and Its Clinical Significance
10.3969/j.issn.1003-4706.2018.03.014
- VernacularTitle:IL-17在肺栓塞合并阻塞性睡眠呼吸暂停低通气综合征患者体内表达情况及其临床意义
- Author:
Yu RAO
1
;
Wen LEI
;
Yue-Qiu LI
;
Mi LI
;
Jian-Qiong FENG
;
An-Min WANG
;
Ying WANG
Author Information
1. 昆明医科大学第二附属医院呼吸内科一病区
- Keywords:
Pulmonary embolism;
Sleep apnea syndromes;
Interleukin-17;
fibrin fragment D
- From:
Journal of Kunming Medical University
2018;39(3):72-76
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the relationship of IL-17 and arterial blood gas, fibrin fragment D (D-D) in patients with both pulmonary embolism (PE) and obstructive sleep apnea-hypopnea syndrome (OSAHS). Methods We collected 20 patients with both PE and OSAHS and 43 patients with only PE who hospitalized in the first ward of pneumology department of the Second Affiliated Hospital of Kunming Medical University, then measured D-D, IL-17 in venous blood and arterial blood gas and recorded them to analysis.Re s ults PO2 in patients with both PE and OSAHS was significantly lower than that in patients with only PE, while D-D and IL-17 of the latter were markedly lesser than the former. Conclus ions The expression of IL-17 between the 2 groups of patients has statistically significant difference. What's more, the expression of IL-17 is positively associated with hypercoagulability and Body Mass Index (BMI), and the result shows a negative relation between arterial blood oxygen partial pressure and IL-17, suggesting that IL-17 may be relate to the common progress of PE and OSASH. Thus, IL-17 can be used in the detection of patients with both PE and OSASH
