Study on the content of aflatoxin Bt in 35 traditional Chinese medicine decoction pieces
10.3760/cma.j.issn.1673-4246.2019.06.015
- VernacularTitle:35种中药饮片黄曲霉毒素B1的含量考察
- Author:
Jinzhi SHEN
1
;
Zheng WANG
;
Yuchun SU
Author Information
1. 厦门大学附属中山医院药学部 361004
- Keywords:
Assay (TCD);
Aflatoxin B1;
Immunoaffinity column;
Photochemical derivatization
- From:
International Journal of Traditional Chinese Medicine
2019;41(6):614-617
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the contamination of aflatoxin B1 in traditional Chinese medicine decoction pieces.and to provide evidence for the development of sdandards and scientific management.Methods Immunoaffinity column and post-column photochemical derivatization were used to detect and quantify aflatoxin B1 in 35 traditional Chinese medicines.Results A total of 48.57％(17 out of 35 batches) traditional Chinese medicine were contained aflatoxin B1.The contents of aflatoxin B1 in all contaminated varieties were less than 1μg/kg,except for Sterculia lychnophorae Semen,Foeniculi Fructus,Corydalis Rhizoma,which exceeded the standard.Conclusions The tested traditional Chinese medicine are highly contaminated of aflatoxin,it is necessary to further study the increase of aflatoxin content under the examination of Chinese Pharmacopoeia Foeniculi Fructus and Corydalis Rhizoma to better control its quality.The degree of aflatoxin B1 pollution is reated to the site of drug use and the place of origin.
