Neuromuscular Blocking Effect of Vecuronium in Electric Burned Patients for Endotracheal Intubation.
10.4097/kjae.1999.36.1.21
- Author:
Sung Jin BAE
1
;
Eun Jung KWON
;
Gyu Jeong NOH
;
Hae Jeong JEONG
;
Hye Jeong LEE
;
Kyu Sam KIM
Author Information
1. Department of Anesthesiology, Hanil Hospital.
- Publication Type:Original Article
- Keywords:
Monitoring, train-of-four;
Neuromuscular relaxants, vecuronium;
Skin, burn
- MeSH:
Anesthesia;
Burns;
Burns, Electric*;
Humans;
Hyperkalemia;
Intubation;
Intubation, Intratracheal*;
Male;
Neuromuscular Blockade*;
Neuromuscular Monitoring;
Relaxation;
Succinylcholine;
Vecuronium Bromide*
- From:Korean Journal of Anesthesiology
1999;36(1):21-26
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: In inducing anesthesia for burn patients, nondepolarizing muscle relaxant (NDMR) is usually used, because succinylcholine, a widely used muscle relaxant may cause hyperkalemia. It is well known that because burn patients show resistance to NDMR, a high dose of NDMR is needed for them. In this study, we wanted to know whether there is significant difference of the relaxation effect between 0.1 mg/Kg and 0.15 mg/Kg dose's of vecuronium, and between burn and unburn patients. METHODS: Subjects are 40 male patients having 1 or 2 ASA physical status (20 are burn patients and the other 20 are unburn patients). We divided them into 4 groups; 1) Group BI (burn patients, vecuronium 0.1 mg/Kg) 2) Group BII (burn Pts, vecuronium 0.15 mg/Kg) 3) Group UBI (unburn Pts, vecuronium 0.1 mg/Kg) 4) Group UBII (unburn Pts, vecuronium 0.15 mg/Kg). Average onset times (time from injection of vecuronium to zero first twitch height (T1)) were measured and intubating condition were scored on 0 to 4 scale. RESULTS: The onset time of vecuronium and distribution of intubation scores didn't show statistical differences among 4 groups. CONCLUSION: The onset time of vecuronium and intubating condition in burn patients dosen't show a difference from unburn patient.
